Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 11130
TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593676BDBM593676(US11578077, Example 71 | 2'-(3-hydroxy-7,7-dimethy...)
Affinity DataKi:  0.0630nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593614BDBM593614(5-hydroxy-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  0.200nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593606BDBM593606(2'-(1'H,3H-spiro[2-benzofuran-1,4'- piperidin]-1'-...)
Affinity DataKi:  0.316nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593639BDBM593639(5,6-difluoro-2'-(1'H,3H-spiro[2- benzofuran-1,4'-p...)
Affinity DataKi:  0.398nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593608BDBM593608(2'-(3,3-dimethyl-1'H,3H-spiro[2- benzofuran-1,4'-p...)
Affinity DataKi:  0.501nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593674BDBM593674(US11578077, Example 69 | 2'-(7,7-dimethyl-1'H,7H- ...)
Affinity DataKi:  0.501nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593643BDBM593643(2'-(5,5-dimethyl-1'H,5H- spiro[furo[3,4-b]pyridine...)
Affinity DataKi:  0.631nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593616BDBM593616(6-hydroxy-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  0.794nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593647BDBM593647(2'-(2-methyl-1'H,5H-spiro[furo[3,4- b]pyridine-7,4...)
Affinity DataKi:  0.794nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593671BDBM593671(US11578077, Example 66 | 1'-[4'-oxo-3,4-dihydro-1H...)
Affinity DataKi:  0.794nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593644BDBM593644(2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine...)
Affinity DataKi:  0.794nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593626BDBM593626(5-methyl-2'-(1'H,3H-spiro[2- benzofuran-1,4'-piper...)
Affinity DataKi:  0.794nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593636BDBM593636(5-chloro-2'-(1'H,3H-spiro[2- benzofuran-1,4'-piper...)
Affinity DataKi:  1nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593635BDBM593635(5-fluoro-2'-(1'H,3H-spiro[2- benzofuran-1,4'-piper...)
Affinity DataKi:  1nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593607BDBM593607(1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3...)
Affinity DataKi:  1nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593669BDBM593669(US11578077, Example 64 | 2'-(1'H,3H-spiro[2-benzof...)
Affinity DataKi:  1nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593646BDBM593646(2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine...)
Affinity DataKi:  1.26nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593620BDBM593620(5-fluoro-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  1.26nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593640BDBM593640(1'-(5,6-difluoro-4'-oxo-1,3-dihydro- 4'H-spiro[ind...)
Affinity DataKi:  1.26nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593627BDBM593627(1'-(5-methyl-4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  1.26nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593670BDBM593670(US11578077, Example 65 | 1'-(4'-oxo-3,4-dihydro-1H...)
Affinity DataKi:  1.58nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593612BDBM593612(6-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  1.58nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593611BDBM593611(5-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  1.58nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593649BDBM593649(2'-(3-methyl-1'H,5H-spiro[furo[3,4- b]pyridine-7,4...)
Affinity DataKi:  2nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593621BDBM593621(7-fluoro-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  2nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593615BDBM593615(6-methoxy-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593629BDBM593629((-)-1'-[5-methyl-4'-oxo-1,3-dihydro- 4'H-spiro[ind...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593622BDBM593622(6-chloro-1'-(4-oxo-1,3-dihydro-4'H- spiro[indene-2...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593641BDBM593641(2'-(1'H,5H-spiro[furo[3,4-b]pyridine- 7,4'-piperid...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593613BDBM593613(5-methoxy-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593677BDBM593677(US11578077, Example 72 | 2'-(2-hydroxy-7,7-dimethy...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593619BDBM593619(4-fluoro-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593651BDBM593651(2'-(6-methyl-1H,1'H-spiro[furo[3,4- c]pyridine-3,4...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593666BDBM593666(US11578077, Example 61 | 2'-(1'H,3H-spiro[2-benzof...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593633BDBM593633(1'-(5-hydroxy-4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  3.98nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593672BDBM593672(US11578077, Example 67 | 1'-[4'-oxo-3,4-dihydro-1H...)
Affinity DataKi:  3.98nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593623BDBM593623(5-bromo-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-2...)
Affinity DataKi:  3.98nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593648BDBM593648(2-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  5.01nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593645BDBM593645(2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine...)
Affinity DataKi:  5.01nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593657BDBM593657(US11578077, Example 52 | 2'-(3-methyl-1'H,7H-spiro...)
Affinity DataKi:  5.01nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593661BDBM593661(US11578077, Example 56 | 2'-(1'H,3H-spiro[2-benzof...)
Affinity DataKi:  6.31nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593618BDBM593618(5,6-dihydroxy-1'-(4'-oxo-1,3-dihydro- 4'H-spiro[in...)
Affinity DataKi:  6.31nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593609BDBM593609(2'-(4-methyl-1'H,3H-spiro[2- benzofuran-1,4'-piper...)
Affinity DataKi:  6.31nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593673BDBM593673(US11578077, Example 68 | 2'-(7,7-dimethyl-1'H,7H- ...)
Affinity DataKi:  7.94nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593655BDBM593655(2'-(6-methyl-1'H,3H-spiro[furo[3,4- c]pyridine-1,4...)
Affinity DataKi:  10nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593610BDBM593610(4-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  10nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593642BDBM593642(2'-(1'H,7H-spiro[furo[3,4-b]pyridine- 5,4'-piperid...)
Affinity DataKi:  10nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593656BDBM593656(6-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  12.6nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593653BDBM593653(2'-(2-methyl-1'H,7H-spiro[furo[3,4- b]pyridine-5,4...)
Affinity DataKi:  12.6nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 593652BDBM593652(6-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  15.8nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

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