Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 11226
TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601386BDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601446BDBM601446(US11634424, Compound 14)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601396BDBM601396(US11634424, Compound 8)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601450BDBM601450(US11634424, Compound 16)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601395BDBM601395(US11634424, Compound 7)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601386BDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601451BDBM601451(US11634424, Compound 17)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601408BDBM601408(US11634424, Compound 12)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601445BDBM601445(US11634424, Compound 13)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601449BDBM601449(US11634424, Compound 15)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601399BDBM601399(US11634424, Compound 10)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601389BDBM601389(US11634424, Compound 20 | US11634424, Compound 2)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601397BDBM601397(US11634424, Compound 9)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601450BDBM601450(US11634424, Compound 16)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601389BDBM601389(US11634424, Compound 20 | US11634424, Compound 2)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601453BDBM601453(US11634424, Compound 19)
Affinity DataIC50: 2nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601393BDBM601393(US11634424, Compound 5)
Affinity DataIC50: 3nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601391BDBM601391(US11634424, Compound 4)
Affinity DataIC50: 3nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601400BDBM601400(US11634424, Compound 11)
Affinity DataIC50: 3nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601390BDBM601390(US11634424, Compound 3)
Affinity DataIC50: 5nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601395BDBM601395(US11634424, Compound 7)
Affinity DataIC50: 13nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601449BDBM601449(US11634424, Compound 15)
Affinity DataIC50: 24nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601389BDBM601389(US11634424, Compound 20 | US11634424, Compound 2)
Affinity DataIC50: 28nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601408BDBM601408(US11634424, Compound 12)
Affinity DataIC50: 32nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601451BDBM601451(US11634424, Compound 17)
Affinity DataIC50: 43nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601399BDBM601399(US11634424, Compound 10)
Affinity DataIC50: 62nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601386BDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 64nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601446BDBM601446(US11634424, Compound 14)
Affinity DataIC50: 73nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601386BDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 79nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601445BDBM601445(US11634424, Compound 13)
Affinity DataIC50: 84nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601400BDBM601400(US11634424, Compound 11)
Affinity DataIC50: 99nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601453BDBM601453(US11634424, Compound 19)
Affinity DataIC50: 166nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601396BDBM601396(US11634424, Compound 8)
Affinity DataIC50: 188nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 257nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601389BDBM601389(US11634424, Compound 20 | US11634424, Compound 2)
Affinity DataIC50: 282nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601391BDBM601391(US11634424, Compound 4)
Affinity DataIC50: 333nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 362nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601393BDBM601393(US11634424, Compound 5)
Affinity DataIC50: 375nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601452BDBM601452(US11634424, Compound 21 | US11634424, Compound 22 ...)
Affinity DataIC50: 386nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601397BDBM601397(US11634424, Compound 9)
Affinity DataIC50: 1.01E+3nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 601390BDBM601390(US11634424, Compound 3)
Affinity DataIC50: 1.97E+3nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent