Compile Data Set for Download or QSAR
Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 11306
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527814BDBM527814((3S,4S)-8-(8-((2- amino-3- chloropyridin-4- yl)thi...)
Affinity DataIC50: 1nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527850BDBM527850((3S,4S)-8-(8-(2,3- dichlorophenyl)-7- methyl- [1,2...)
Affinity DataIC50: 10nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605733BDBM605733(US11673901, Compound 4 | US11673901, Example 4)
Affinity DataIC50: 29nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605786BDBM605786(US11673901, Compound 56)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605785BDBM605785(US11673901, Compound 55)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605784BDBM605784(US11673901, Compound 54)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605791BDBM605791(US11673901, Compound 61)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527814BDBM527814((3S,4S)-8-(8-((2- amino-3- chloropyridin-4- yl)thi...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605794BDBM605794(US11673901, Compound 64)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605793BDBM605793(US11673901, Compound 63)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605792BDBM605792(US11673901, Compound 62)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605733BDBM605733(US11673901, Compound 4 | US11673901, Example 4)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605771BDBM605771(US11673901, Compound 41)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605770BDBM605770(US11673901, Compound 40)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605769BDBM605769(US11673901, Compound 39)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605768BDBM605768(US11673901, Compound 38)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605775BDBM605775(US11673901, Compound 45)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605774BDBM605774(US11673901, Compound 44)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605773BDBM605773(US11673901, Compound 43)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605772BDBM605772(US11673901, Compound 42)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605779BDBM605779(US11673901, Compound 49)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605778BDBM605778(US11673901, Compound 48)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605777BDBM605777(US11673901, Compound 47)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605776BDBM605776(US11673901, Compound 46)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605783BDBM605783(US11673901, Compound 53)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605782BDBM605782(US11673901, Compound 52)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605780BDBM605780(US11673901, Compound 50)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605759BDBM605759(US11673901, Compound 29)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605763BDBM605763(US11673901, Compound 33)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605762BDBM605762(US11673901, Compound 32)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605761BDBM605761(US11673901, Compound 31)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605760BDBM605760(US11673901, Compound 30)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605767BDBM605767(US11673901, Compound 37)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605766BDBM605766(US11673901, Compound 36)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605765BDBM605765(US11673901, Compound 35)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605764BDBM605764(US11673901, Compound 34)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605739BDBM605739(US11673901, Compound 9)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527761BDBM527761((3S,4S)-8-(8-(2,3- dichlorophenyl)-7- methylimidaz...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527850BDBM527850((3S,4S)-8-(8-(2,3- dichlorophenyl)-7- methyl- [1,2...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605743BDBM605743(US11673901, Compound 13)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605742BDBM605742(US11673901, Compound 12)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527838BDBM527838((3S,4S)-8-(8- ((2,3- dichlorophenyl) thio)imidazo[...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605740BDBM605740(US11673901, Compound 10)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605747BDBM605747(US11673901, Compound 17)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527913BDBM527913((3S,4S)-8-(8-((1H- pyrrolo[2,3- b]pyridin-4- yl)th...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605813BDBM605813(US11673901, Compound 83)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 527819BDBM527819(1-(8-((2,3- dichlorophenyl)thio) imidazo[1,2- c]py...)
Affinity DataIC50: 120nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605787BDBM605787(US11673901, Compound 57)
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605755BDBM605755(US11673901, Compound 25)
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 605754BDBM605754(US11673901, Compound 24)
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

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