Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 11418
TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606735(CHEMBL5219718 | US11731973, Example 3)
Affinity DataKi:  0.300nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606737(CHEMBL5218727 | US11731973, Example 5)
Affinity DataKi:  0.400nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606738(CHEMBL5218590 | US11731973, Example 6)
Affinity DataKi:  0.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606740(CHEMBL5220536 | US11731973, Example 30)
Affinity DataKi:  0.580nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606742(CHEMBL5220948 | US11731973, Example 9)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613740(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbutyl)-...)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606739(CHEMBL5220152 | US11731973, Example 7)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606741(CHEMBL5219710 | US11731973, Example 1)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50606736(CHEMBL5218916 | US11731973, Example 10)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613743(1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-...)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613734(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-((S)-1,3-di...)
Affinity DataKi:  1nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613746(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-y...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613745((+)-3-(2-aminobenzoxazol-5-yl)-1- ((S)-2-methyl-2-...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613744(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-e...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613736(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-(1-methylcy...)
Affinity DataKi:  1.40nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613748(3-[4,6-diamino-3-(2- aminobenzoxazol-5-yl)pyrazolo...)
Affinity DataKi:  1.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613749(3-(2-aminobenzoxazol-5-yl)-1-(2- methyl-2-methylsu...)
Affinity DataKi:  1.70nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613750(3-(2-amino-4-chlorobenzoxazol-5-yl)- 1-(2,2-dimeth...)
Affinity DataKi:  1.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613751(3-(2-amino-6-methoxybenzoxazol-5- yl)-1-(2,2-dimet...)
Affinity DataKi:  2.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613752(2-[4,6-diamino-1-(2,2- dimethylpropyl)-1H-pyrazolo...)
Affinity DataKi:  2.30nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613753(3-(2-amino-6-methoxybenzoxazol-5- yl)-1-(2,2-dimet...)
Affinity DataKi:  2.90nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50529395(CHEMBL4529672 | US11731973, Example 21)
Affinity DataKi:  3.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613755(3-(2-aminobenzoxazol-5-yl)-1-(2- ethyl-2-methanesu...)
Affinity DataKi:  3.90nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613756(3-(2-aminobenzoxazol-5-yl)-4-chloro- 1-isobutyl-1H...)
Affinity DataKi:  5.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50529393(CHEMBL4564479 | US11731973, Example 24)
Affinity DataKi:  6.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613758(3-(2-amino-6-chlorobenzoxazol-5-yl)- 1-((S)-1,2-di...)
Affinity DataKi:  8.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM50529398(CHEMBL4549761 | US11731973, Example 31)
Affinity DataKi:  10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613759(3-(2-aminobenzoxazol-5-yl)-1- isopropyl-N*6*-methy...)
Affinity DataKi:  13.4nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613760(5-(6-amino-4-methyl-1-neopentyl- 1H-pyrazolo[3,4-d...)
Affinity DataKi:  14.3nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613761(3-(2-cyclopropylaminobenzoxazol-5- yl)-1-isopropyl...)
Affinity DataKi:  21nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613762(3-(2-amino-7-methylbenzoxazol-5- yl)-1-(2,2-dimeth...)
Affinity DataKi:  102nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent