Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 12158
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642875BDBM642875((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 10nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642880BDBM642880((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(Ben...)
Affinity DataIC50: 12.6nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642882BDBM642882((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-((Cy...)
Affinity DataIC50: 20nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642894BDBM642894((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-Acet...)
Affinity DataIC50: 31.6nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642889BDBM642889((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-acet...)
Affinity DataIC50: 31.6nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642893BDBM642893((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-acet...)
Affinity DataIC50: 63.1nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642901BDBM642901((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50: 63.1nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642892BDBM642892((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 79.4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642877BDBM642877((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 100nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642909BDBM642909((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 126nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642913BDBM642913((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[4-(...)
Affinity DataIC50: 126nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 683068BDBM683068(US20240209019, Compound 258-2 | (2S,4aS,6aS,6bR,8a...)
Affinity DataIC50: 126nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 683099BDBM683099(US20240209019, Compound 605-2 | 2-(3-((1-PEG5K -1H...)
Affinity DataIC50: 126nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642898BDBM642898((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(2-H...)
Affinity DataIC50: 158nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642907BDBM642907((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-((me...)
Affinity DataIC50: 200nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642891BDBM642891((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 200nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642879BDBM642879((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ben...)
Affinity DataIC50: 251nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642911BDBM642911((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-((di...)
Affinity DataIC50: 251nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642890BDBM642890((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 251nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642886BDBM642886((2S,4aS,6aS,6bR,8aR,9S,10R,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 398nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642884BDBM642884((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(Met...)
Affinity DataIC50: 398nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642876BDBM642876((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642876BDBM642876((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642872BDBM642872((2S,4aS,6aS,6bR,8aS,10S,12aS,12bR,14bR)-2,4a,6a,6b...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 683054BDBM683054(US20240209019, Compound 178-1 | (2S,4aS,6aS,6bR,8a...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642888BDBM642888((2S,4aS,6aS,6bR,8aR,9S,10R,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642900BDBM642900((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50: 501nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642887BDBM642887((2S,4aS,6aS,6bR,8aR,9S,10R,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 794nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642873BDBM642873((2S,4aS,6aS,6bR,8aS,10S,12aS,12bR,14bR)-2,4a,6a,6b...)
Affinity DataIC50: 794nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642903BDBM642903((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-2,4a,6a,6b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642885BDBM642885((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50: 1.26E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642897BDBM642897((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50: 1.26E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642881BDBM642881((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(cyc...)
Affinity DataIC50: 1.59E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642904BDBM642904((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-(2-{[5-...)
Affinity DataIC50: 1.59E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642912BDBM642912((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[4-(...)
Affinity DataIC50: 2.51E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642870BDBM642870((2S,4aS,6aS,6bR,8aS,10S,12aS,12bR,14bR)-2,4a,6a,6b...)
Affinity DataIC50: 3.16E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642902BDBM642902((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-(carbox...)
Affinity DataIC50: 3.98E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642874BDBM642874((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 3.98E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642883BDBM642883((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(met...)
Affinity DataIC50: 7.94E+3nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642910BDBM642910((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-{[2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642896BDBM642896((2S,4aS,6aS,6bR,8aR,9R,10S,12aS,12bR,14bR)-10-Hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642895BDBM642895((2S,4aS,6aS,6bR,9R,10S,12aS,12bR,14bR)-9-[(carboxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642906BDBM642906((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642905BDBM642905((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-2,4a,6a,6b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642908BDBM642908((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642878BDBM642878((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642914BDBM642914((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 642899BDBM642899((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were diluted in DMSO and serial dilutions prepared by titrating in DMSO. Compounds were then diluted into DMEM/F12. Transwell plates contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent