Compile Data Set for Download or QSAR
Report error Found 234 Enz. Inhib. hit(s) with all data for entry = 9997
TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792593BDBM792593(US20260042753, Compound A232)
Affinity DataIC50: 0.0900nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792527BDBM792527(2-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.290nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792583BDBM792583((cis)-5-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-ind...)
Affinity DataIC50: 0.320nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792457BDBM792457(3-(3-{4-[(cis)-4-methyl-octahydro-1H-pyrrolo[3,2-b...)
Affinity DataIC50: 0.350nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792463BDBM792463(4-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.370nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792455BDBM792455(5-fluoro-6-(2-methoxyethoxy)-3-{3-[4-(4-methyl-1,4...)
Affinity DataIC50: 0.390nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792542BDBM792542((4-{5-[5-chloro-6-(2-methoxy-ethoxy)-1H-indazol-3-...)
Affinity DataIC50: 0.400nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792603BDBM792603(3-{3-[4-(3,3-dimethyl-piperidin-4-yl)-phenyl]-isox...)
Affinity DataIC50: 0.400nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792488BDBM792488(7-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.440nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792523BDBM792523(7-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.440nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792577BDBM792577(3-(3-{4-[(cis)-octahydropyrano[3,4-c]pyrrole-2-car...)
Affinity DataIC50: 0.440nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792553BDBM792553(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[3-(pyridin-3...)
Affinity DataIC50: 0.450nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792530BDBM792530(5-fluoro-6-(2-methoxyethoxy)-3-[3-(4-{6-oxa-3-azab...)
Affinity DataIC50: 0.450nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792525BDBM792525(5-fluoro-6-(2-methoxyethoxy)-3-[3-(4-{2-oxa-6-azas...)
Affinity DataIC50: 0.460nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792389BDBM792389(N-{[(2S)-1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-...)
Affinity DataIC50: 0.470nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792575BDBM792575(5-fluoro-6-(2-methoxyethoxy)-3-[3-(4-{1-methyl-1H,...)
Affinity DataIC50: 0.490nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792486BDBM792486(2-[(2S)-1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-i...)
Affinity DataIC50: 0.510nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792592BDBM792592({[1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol...)
Affinity DataIC50: 0.520nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792538BDBM792538(2-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.530nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792496BDBM792496((4-{5-[5-chloro-6-(2-methoxy-ethoxy)-1H-indazol-3-...)
Affinity DataIC50: 0.530nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792534BDBM792534(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[(1R,4R)-2-ox...)
Affinity DataIC50: 0.540nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792590BDBM792590(1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.540nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792554BDBM792554(5-fluoro-6-(2-methoxyethoxy)-3-[3-(4-{1H,2H,3H-pyr...)
Affinity DataIC50: 0.550nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792378BDBM792378(2-[(2S)-1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-i...)
Affinity DataIC50: 0.550nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792387BDBM792387((cis)-1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-ind...)
Affinity DataIC50: 0.570nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792397BDBM792397(N-{[(2R)-1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-...)
Affinity DataIC50: 0.580nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792573BDBM792573(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[3-(pyrimidin...)
Affinity DataIC50: 0.590nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792547BDBM792547(3-(3-{4-[4-(cyclopropylmethyl)piperazine-1-carbony...)
Affinity DataIC50: 0.590nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792451BDBM792451(4-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.600nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792591BDBM792591(5-fluoro-6-(2-methoxy-ethoxy)-3-{3-[4-(1,3,3-trime...)
Affinity DataIC50: 0.610nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792564BDBM792564(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[4-(oxan-4-yl...)
Affinity DataIC50: 0.610nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792585BDBM792585(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[3-(1-methyl-...)
Affinity DataIC50: 0.620nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792379BDBM792379(5-fluoro-3-(3-{4-[3-(1H-imidazol-1-yl)azetidine-1-...)
Affinity DataIC50: 0.630nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792449BDBM792449(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[3-(pyridin-4...)
Affinity DataIC50: 0.640nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792500BDBM792500((4-{5-[5-chloro-6-(2-methoxy-ethoxy)-1H-indazol-3-...)
Affinity DataIC50: 0.650nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792532BDBM792532(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[(1S,4S)-2-ox...)
Affinity DataIC50: 0.650nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792580BDBM792580(1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.670nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792507BDBM792507(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[3-(pyridin-2...)
Affinity DataIC50: 0.690nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792421BDBM792421([(3S)-4-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-ind...)
Affinity DataIC50: 0.700nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792511BDBM792511(6-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.710nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792452BDBM792452(3-{3-[4-(1,4-diazepan-1-yl)phenyl]-1,2-oxazol-5-yl...)
Affinity DataIC50: 0.730nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792428BDBM792428(4-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.730nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792476BDBM792476([1-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-...)
Affinity DataIC50: 0.730nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792478BDBM792478(5-fluoro-3-(3-{4-[(2R)-2-(methanesulfonylmethyl)py...)
Affinity DataIC50: 0.730nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792584BDBM792584(5-fluoro-6-(2-methoxyethoxy)-3-[3-(4-{1H,4H,5H,6H-...)
Affinity DataIC50: 0.740nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792382BDBM792382(5-fluoro-3-(3-{4-[(2S)-2-(methanesulfonylmethyl)py...)
Affinity DataIC50: 0.75nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792567BDBM792567(2-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.760nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792524BDBM792524(4-(4-{5-[5-fluoro-6-(2-methoxyethoxy)-1H-indazol-3...)
Affinity DataIC50: 0.760nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792429BDBM792429(5-fluoro-6-(2-methoxyethoxy)-3-(3-{4-[(3S)-3-(meth...)
Affinity DataIC50: 0.760nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 792579BDBM792579(3-(3-{4-[(cis)-octahydrofuro[3,4-c]pyridine-5-carb...)
Affinity DataIC50: 0.760nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

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