Compile Data Set for Download or QSAR
Report error Found 413 Enz. Inhib. hit(s) with all data for entry = 13581
TargetRibosomal protein S6 kinase alpha-3(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50524300BDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 2nMAssay Description:Table 24: Selected compounds of the invention were tested for their inhibitory potential of RSK1, RSK2, RSK3 and RSK4 kinases via the Eurofins Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-2 (RSK3)(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50524300BDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 4nMAssay Description:Table 24: Selected compounds of the invention were tested for their inhibitory potential of RSK1, RSK2, RSK3 and RSK4 kinases via the Eurofins Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-6(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50524300BDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 5nMAssay Description:Table 24: Selected compounds of the invention were tested for their inhibitory potential of RSK1, RSK2, RSK3 and RSK4 kinases via the Eurofins Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667723BDBM50667723(CHEMBL6189671 | US20260132140, Example 98)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807999BDBM807999((R)-5-((1-(4-(3- (Ethylamino)pyrrolidin- 1-yl)phen...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 808001BDBM808001(5-((1-(4-((3R,4S)-3- Fluoro-4- (methylamino) pyrro...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667703BDBM50667703(CHEMBL6192277 | US20260132140, Example 37)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807938BDBM807938(5-((1-(4-((3aR,6aS)-5- Methylhexahydropyrrolo [3,4...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 808002BDBM808002(5-((1-(4-((2R,4R)-4- Amino-2- methylpyrrolidin-1- ...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807940BDBM807940((R)-5-((1-(4-(3- (Azetidin-1- yl)pyrrolidin-1-yl)-...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667702BDBM50667702(CHEMBL6192068 | US20260132140, Example 40)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667720BDBM50667720(CHEMBL6193468 | US20260132140, Example 89)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807991BDBM807991((R)-5-((1-(4-(7- Amino-5- azaspiro[2.4]heptan- 5-y...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807864BDBM807864(5-((1-(4-(4- Ethylpiperazin-1-yl)-2- methoxyphenyl...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807929BDBM807929(5-((1-(4-((3R,4S)-3- Fluoro-4- (methylamino)pyrrol...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807994BDBM807994(5-((1-(4-((3S,4R)-3- Amino-4- fluoropyrrolidin-1- ...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807867BDBM807867((S)-5-((1-(4- (Hexahydropyrrolo[1,2- a]pyrazin-2(1...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667704BDBM50667704(CHEMBL6191594 | US20260132140, Example 32)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807921BDBM807921((R)-5-((1-(4-(3- (Bis(methyl- d3)amino)pyrrolidin-...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807922BDBM807922(5-((1-(5-((2R,4R)-4- (Dimethylamino)-2- methylpyrr...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667715BDBM50667715(CHEMBL6191934 | US20260132140, Example 73)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667717BDBM50667717(CHEMBL6188848 | US20260132140, Example 74)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807975BDBM807975(US20260132140, Example 138)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667716BDBM50667716(CHEMBL6190549 | US20260132140, Example 75)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667707BDBM50667707(CHEMBL6192659 | US20260132140, Example 12)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807977BDBM807977(US20260132140, Example 140)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667713BDBM50667713(CHEMBL6190328 | US20260132140, Example 78)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807916BDBM807916((R)-5-((1-(4-(3- (Dimethylamino) pyrrolidin-1-yl)-...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807838BDBM807838(5-((1-(4-((1R,5R)-6-Methyl-3,6-diazabicyclo[3.2.0]...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667711BDBM50667711(CHEMBL6192099 | US20260132140, Example 65)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667689BDBM50667689(CHEMBL6188771 | US20260132140, Example 3)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807970BDBM807970(5-((1-(4-(3-(3- Isopropylazetidin-1- yl)pyrrolidin...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807958BDBM807958(5-((1-(4-(3- (Dimethylamino) piperidin-1- yl)phen...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807896BDBM807896((R)-5-((1-(5-(3- (Dimethylamino) pyrrolidin-1-yl)-...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667719BDBM50667719(CHEMBL6189190 | US20260132140, Example 63)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667708BDBM50667708(CHEMBL6191997 | US20260132140, Example 50)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807951BDBM807951(US20260132140, Example 114)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807888BDBM807888((R)-5-((1-(4-([1,3'- Bipyrrolidin]-1'-yl)-2- metho...)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807879BDBM807879(5-((1-(4-((1S,4S)-5- Methyl-2,5- diazabicyclo[2.2....)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 50667710BDBM50667710(CHEMBL6191521 | US20260132140, Example 47)
Affinity DataIC50: 10nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807998BDBM807998(5-((1-(4-((1R,5R)-3,6- Diazabicyclo[3.2.0] heptan-...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807871BDBM807871(5-((1-(3-(5-Methyl-2,5- diazaspiro[3.4]octan-2- yl...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 808000BDBM808000(5-((1-(4-((3R,4S)-3- Methoxy-4- (methylamino)pyrro...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807875BDBM807875((R)-5-((1-(3-(3- (Dimethylamino) pyrrolidin- 1-yl)...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807876BDBM807876(5-((1-(3-(8-Methyl-2,8- diazaspiro[4.5]decan- 2-yl...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807990BDBM807990((R)-5-((1-(4-(3- Aminopyrrolidin-1- yl)phenyl)-1H-...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807863BDBM807863(5-((1-(4-((1- Methylpiperidin-4- yl)amino)phenyl)-...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807865BDBM807865(5-((1-(3-Methyl-4-(4- methylpiperazin-1- yl)phenyl...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807993BDBM807993((R)-5-((1-(4-(3-Amino- 3-methylpyrrolidin-1- yl)ph...)
Affinity DataIC50: 18nMAssay Description:Table 20: 2 μL enzyme/substrate solution (1 nM Chk-1 (Carna Bioscience #02-177), in solution with 30 μM ATP, 4 μM STK1 S1 (Cisbio #62ST1PEB) in assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

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