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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 6876
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155374(US9006282, Example 2, Compound 2 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155389(US9006282, Example 3, Compound 8)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155390(US9006282, Example 3, Compound 9)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155376(US9006282, Example 2, Compound 4 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155384(US9006282, Example 3, Compound 3)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155385(US9006282, Example 3, Compound 4)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155386(US9006282, Example 3, Compound 5)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155380(US9006282, Example 2, Compound 8 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155382(US9006282, Example 2, Compound 10 | US9102656, Exa...)
Affinity DataIC50: 2nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155379(US9006282, Example 2, Compound 7 | US9102656, Exam...)
Affinity DataIC50: 2nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155381(US9006282, Example 2, Compound 9 | US9102656, Exam...)
Affinity DataIC50: 2nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155388(US9006282, Example 3, Compound 7)
Affinity DataIC50: 3nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 3nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155378(US9006282, Example 2, Compound 6 | US9102656, Exam...)
Affinity DataIC50: 3nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155377(US9006282, Example 2, Compound 5 | US9102656, Exam...)
Affinity DataIC50: 4nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155387(US9006282, Example 3, Compound 6)
Affinity DataIC50: 4nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM50371228(Crestor | Rosuvastatin | ROSUVASTATIN CALCIUM | US...)
Affinity DataIC50: 4nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM50221993(calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fl...)
Affinity DataIC50: 7nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155375(US9006282, Example 2, Compound 3 | US9102656, Exam...)
Affinity DataIC50: 8nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155383(US9006282, Example 2, Compound 11 | US9102656, Exa...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent