Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 6900
TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158161(US9029360, 4)
Affinity DataIC50: 33nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158163(US9029360, 6)
Affinity DataIC50: 43nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158167(US9029360, 10)
Affinity DataIC50: 59nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50: 63nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50: 66nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158162(US9029360, 5)
Affinity DataIC50: 110nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158176(US9029360, 19)
Affinity DataIC50: 128nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158158(US9029360, 1)
Affinity DataIC50: 146nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158169(US9029360, 12)
Affinity DataIC50: 148nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158159(US9029360, 2)
Affinity DataIC50: 230nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158175(US9029360, 18)
Affinity DataIC50: 235nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158164(US9029360, 7)
Affinity DataIC50: 340nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158174(US9029360, 17)
Affinity DataIC50: 550nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158171(US9029360, 14)
Affinity DataIC50: 603nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158172(US9029360, 15)
Affinity DataIC50: 692nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50: 1.29E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158160(US9029360, 3)
Affinity DataIC50: 1.39E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158166(US9029360, 9)
Affinity DataIC50: 1.42E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158165(US9029360, 8)
Affinity DataIC50: 1.55E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158160(US9029360, 3)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158161(US9029360, 4)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158162(US9029360, 5)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158163(US9029360, 6)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158158(US9029360, 1)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158159(US9029360, 2)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158169(US9029360, 12)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158171(US9029360, 14)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158164(US9029360, 7)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158165(US9029360, 8)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158166(US9029360, 9)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158167(US9029360, 10)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158172(US9029360, 15)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158174(US9029360, 17)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent