Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8116
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432559(CHEMBL2347008 | US9353061, Atorva-HA (5))
Affinity DataIC50: 9.20nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432560(CHEMBL2347007 | US9353061, Simva-HA (2))
Affinity DataIC50: 11.4nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 11.6nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 16.8nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 19.4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20.9nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 29.5nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432558(CHEMBL2347009 | US9353061, Rosuva-HA (7))
Affinity DataIC50: 43.7nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 50.5nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 60.1nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432560(CHEMBL2347007 | US9353061, Simva-HA (2))
Affinity DataIC50: 60.7nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432560(CHEMBL2347007 | US9353061, Simva-HA (2))
Affinity DataIC50: 67.1nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432559(CHEMBL2347008 | US9353061, Atorva-HA (5))
Affinity DataIC50: 83.7nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 101nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432559(CHEMBL2347008 | US9353061, Atorva-HA (5))
Affinity DataIC50: 118nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432558(CHEMBL2347009 | US9353061, Rosuva-HA (7))
Affinity DataIC50: 125nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432558(CHEMBL2347009 | US9353061, Rosuva-HA (7))
Affinity DataIC50: 133nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432560(CHEMBL2347007 | US9353061, Simva-HA (2))
Affinity DataIC50: 414nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432559(CHEMBL2347008 | US9353061, Atorva-HA (5))
Affinity DataIC50: 467nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 468nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432558(CHEMBL2347009 | US9353061, Rosuva-HA (7))
Affinity DataIC50: 600nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 1.11E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.12E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 1.42E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.63E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 2.25E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 2.59E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent