Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 8554
Target5-hydroxytryptamine receptor 2C(Human)
Ixaltis

US Patent
LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  200nM IC50: 250nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Ixaltis

US Patent
LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  620nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Ixaltis

US Patent
LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  720nM IC50: 1.40E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Ixaltis

US Patent
LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  980nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  1.60E+3nM IC50: 4.70E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Human)
Ixaltis

US Patent
LigandPNGBDBM50278564(Litoxetine | CHEMBL471036 | US9511061, Compound A)
Affinity DataKi:  2.60E+3nM IC50: 7.20E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent