Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4E-binding protein 1
Ligand
BDBM545578
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
IC50
1.52±n/a nM
Citation
Sperry, S; Xiang, AX; Ernst, JT; Reich, SH; Sprengeler, PA; Shaghafi, M; Michels, T; Nilewski, C; Tran, CV; Packard, GK; Grubbs, A; Urkalan, K; Mukaiyama, T EIF4E-inhibiting compounds and methods US Patent US11286268 Publication Date 3/29/2022
More Info.:
Target
Name:
Eukaryotic translation initiation factor 4E-binding protein 1
Synonyms:
4EBP1_HUMAN | EIF4EBP1 | GFP-4EBP | GFP-4EBP1 | Green fluorescent protein-Eukaryotic initiation factor 4E (eIF4E) binding protein
Type:
Fusion protein
Mol. Mass.:
12578.35
Organism:
Human
Description:
n/a
Residue:
118
Sequence:
MSGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI