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Target
Transcription factor SOX-18
Ligand
BDBM223295
Substrate
n/a
Meas. Tech.
Inhibition of Sox18-DNA Binding Assay
IC50
327000±1100 nM
Citation
 FRANCOIS, M; ZUEGG, J; OVERMAN, J; MAMIDYALA, SK; SALIM, AA; FONTAINE, FR; COOPER, MA; CAPON, RJ; ROBERTSON, AA COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT US Patent  US20240002326 Publication Date 1/4/2024 
Target
Name:
Transcription factor SOX-18
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
40895.30
Organism:
Human
Description:
P35713
Residue:
384
Sequence:
MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG
  
Inhibitor
Name:
BDBM223295
Synonyms:
Sm8 | US20240002326, Compound Sm8
Type:
Small organic molecule
Emp. Form.:
C20H24O3
Mol. Mass.:
312.4028
SMILES:
COc1cccc(CCCCCCc2ccccc2)c1C(O)=O
Structure:
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