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Target
Mu-type opioid receptor
Ligand
BDBM50008980
Substrate
n/a
Meas. Tech.
ChEBML_146241
IC50
5.4±n/a nM
Citation
 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics. J Med Chem 34:827-41 (1991) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50008980
Synonyms:
4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl)-piperidine-4-carboxylic acid methyl ester | CHEMBL169366
Type:
Small organic molecule
Emp. Form.:
C21H28N4O3
Mol. Mass.:
384.472
SMILES:
CCC(=O)N(c1ccccc1)C1(CCN(CCn2cccn2)CC1)C(=O)OC
Structure:
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