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Found 48 with Last Name = 'bagley' and Initial = 'jr'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  1.10nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017412(CHEMBL345120 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi:  1.90nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataKi:  2.20nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017406(CHEMBL162700 | Furan-3-carboxylic acid benzo[1,2,5...)
Affinity DataKi:  2.60nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017416(CHEMBL347188 | Furan-2-carboxylic acid (4-methyl-p...)
Affinity DataKi:  4.10nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017404(CHEMBL161084 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi:  7.5nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017420(CHEMBL157922 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi:  7.70nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017403(CHEMBL161442 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi:  8.40nMAssay Description:The ability of the compound to displace [3H]-naloxone from the opioid receptor mu isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017405(2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-pyridin...)
Affinity DataKi:  13nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017411(CHEMBL158857 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi:  14nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017410(2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-pyrimid...)
Affinity DataKi:  16nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017409(CHEMBL161023 | Furan-2-carboxylic acid (6-chloro-p...)
Affinity DataKi:  19nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017414(CHEMBL161147 | Furan-3-carboxylic acid (2-chloro-p...)
Affinity DataKi:  21nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017413(CHEMBL161082 | Furan-2-carboxylic acid (2-chloro-p...)
Affinity DataKi:  22nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017402(CHEMBL158856 | Furan-3-carboxylic acid (1-phenethy...)
Affinity DataKi:  35nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017400(CHEMBL352442 | Furan-3-carboxylic acid (2-chloro-p...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017419(2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-piperid...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017415(CHEMBL161487 | Furan-2-carboxylic acid morpholin-4...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017417(CHEMBL347810 | Furan-3-carboxylic acid (6-chloro-p...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017408(CHEMBL351672 | Furan-3-carboxylic acid (1-phenethy...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017407(CHEMBL161057 | Furan-3-carboxylic acid (6-chloro-p...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= absolutely no % changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017397(1-Phenethyl-piperidin-4-ylamine | CHEMBL423430)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017401(CHEMBL422180 | Furan-3-carboxylic acid (1-phenethy...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017418(CHEMBL161512 | Furan-2-carboxylic acid (1-phenethy...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the opioid receptor mu isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017398(2-Methoxy-N-morpholin-4-yl-N-(1-phenethyl-piperidi...)
Affinity DataKi: >100nMAssay Description:The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Boc Technical Center

Curated by ChEMBL
LigandPNGBDBM50017399(CHEMBL161280 | N-(6-Chloro-pyrimidin-4-yl)-2-metho...)
Affinity DataKi:  214nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataIC50:  3.10nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008980(4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...)
Affinity DataIC50:  5.40nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008982(CHEMBL168723 | N-[4-Methoxymethyl-1-(2-pyrazol-1-y...)
Affinity DataIC50:  10nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM83450(ALFENTANIL | Alfentanil hydrochloride | MLS0023206...)
Affinity DataIC50:  15nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataIC50:  187nMAssay Description:In vitro binding activity against opioid receptor delta using [3DPDPE] as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008980(4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...)
Affinity DataIC50:  809nMAssay Description:In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008983(1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008981(CHEMBL169587 | N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoi...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008982(CHEMBL168723 | N-[4-Methoxymethyl-1-(2-pyrazol-1-y...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataIC50:  5.89E+3nMAssay Description:In vitro binding activity against opioid receptor kappa using [3H]-EKC as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Anaquest

Curated by ChEMBL
LigandPNGBDBM83450(ALFENTANIL | Alfentanil hydrochloride | MLS0023206...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008981(CHEMBL169587 | N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoi...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008983(1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227468(CHEMBL33879)
Affinity DataEC50:  10nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227469(CHEMBL285536)
Affinity DataEC50:  170nMAssay Description:In vitro displacement of 3 nM [3H]4-hydroxytamoxifen from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  5.70nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227470(CHEMBL34648)
Affinity DataEC50:  4.5nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227471(CHEMBL287352)
Affinity DataEC50:  3.30nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50023749(4-(1,2-diphenyl-vinyl)-phenol | 4-[1-(4-hydroxyphe...)
Affinity DataEC50:  3.20nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataEC50:  6nMAssay Description:In vitro displacement of 3 nM [3H]4-hydroxytamoxifen from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227471(CHEMBL287352)
Affinity DataEC50:  9.5nMAssay Description:In vitro displacement of 3 nM [3H]4-hydroxytamoxifen from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50227469(CHEMBL285536)
Affinity DataEC50:  2.90nMAssay Description:In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed