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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50268630
Substrate
n/a
Meas. Tech.
ChEMBL_1705247 (CHEMBL4056480)
EC50
586±n/a nM
Citation
 Koshizawa, T; Morimoto, T; Watanabe, G; Watanabe, T; Yamasaki, N; Sawada, Y; Fukuda, T; Okuda, A; Shibuya, K; Ohgiya, T Optimization of a novel series of potent and orally bioavailable GPR119 agonists. Bioorg Med Chem Lett 27:3249-3253 (2017) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Human
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50268630
Synonyms:
CHEMBL4086445
Type:
Small organic molecule
Emp. Form.:
C26H28N6O4S
Mol. Mass.:
520.603
SMILES:
CC(O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Structure:
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