Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50218116
Substrate
n/a
Meas. Tech.
ChEMBL_1742213 (CHEMBL4157963)
IC50
1580±n/a nM
Citation
 Hassan, AHE; Cho, MC; Kim, HI; Yang, JS; Park, KT; Hwang, JY; Jang, CG; Park, KD; Lee, YS Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB Bioorg Med Chem 26:5069-5078 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50218116
Synonyms:
CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C26H24O2
Mol. Mass.:
368.4676
SMILES:
CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: