Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50042162
Substrate
n/a
Meas. Tech.
ChEBML_153299
Ki
232±n/a nM
Citation
 Daines, RA; Chambers, PA; Pendrak, I; Jakas, DR; Sarau, HM; Foley, JJ; Schmidt, DB; Kingsbury, WD Trisubstituted pyridine leukotriene B4 receptor antagonists: synthesis and structure-activity relationships. J Med Chem 36:3321-32 (1993) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50042162
Synonyms:
3-{6-(3-Methoxy-benzenesulfinylmethyl)-3-[8-(4-methoxy-phenyl)-octyloxy]-pyridin-2-yl}-acrylic acid | CHEMBL113167
Type:
Small organic molecule
Emp. Form.:
C31H37NO6S
Mol. Mass.:
551.694
SMILES:
COc1ccc(CCCCCCCCOc2ccc(CS(=O)c3cccc(OC)c3)nc2C=CC(O)=O)cc1 |w:33.35|
Structure:
Search PDB for entries with ligand similarity: