Target
Chymotrypsinogen A
Ligand
BDBM50067898
Substrate
n/a
Meas. Tech.
ChEMBL_34119 (CHEMBL649747)
IC50
>100000±n/a nM
Citation
 Weston, GSBlázquez, JBaquero, FShoichet, BK Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase. J Med Chem 41:4577-86 (1998) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50067898
Synonyms:
3-(5-(dimethylamino)naphthalene-1-sulfonamido)phenylboronic acid | CHEMBL140740 | m(dansylamidophenyl)boronic acid
Type:
Small organic molecule
Emp. Form.:
C18H19BN2O4S
Mol. Mass.:
370.23
SMILES:
CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cccc(c1)B(O)O
Structure:
Search PDB for entries with ligand similarity: