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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50554669
Substrate
n/a
Meas. Tech.
ChEMBL_2050195 (CHEMBL4704894)
EC50
400±n/a nM
Citation
 Peiretti, F; Montanari, R; Capelli, D; Bonardo, B; Colson, C; Amri, EZ; Grimaldi, M; Balaguer, P; Ito, K; Roeder, RG; Pochetti, G; Brunel, JM A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor ? Binding Properties and Biological Activities. J Med Chem 63:13124-13139 (2020) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50554669
Synonyms:
CHEMBL4743677
Type:
Small organic molecule
Emp. Form.:
C20H31NO4
Mol. Mass.:
349.4644
SMILES:
CCCCCCCCOc1ccc(cc1)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Structure:
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