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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50554669
Substrate
n/a
Meas. Tech.
ChEMBL_2050207 (CHEMBL4704906)
Kd
3100±n/a nM
Citation
 Peiretti, F; Montanari, R; Capelli, D; Bonardo, B; Colson, C; Amri, EZ; Grimaldi, M; Balaguer, P; Ito, K; Roeder, RG; Pochetti, G; Brunel, JM A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor ? Binding Properties and Biological Activities. J Med Chem 63:13124-13139 (2020) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Human
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM50554669
Synonyms:
CHEMBL4743677
Type:
Small organic molecule
Emp. Form.:
C20H31NO4
Mol. Mass.:
349.4644
SMILES:
CCCCCCCCOc1ccc(cc1)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Structure:
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