Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50118529
Substrate
n/a
Meas. Tech.
ChEMBL_37198 (CHEMBL650799)
Ki
0.92±n/a nM
Citation
Campiani, G; Ramunno, A; Fiorini, I; Nacci, V; Morelli, E; Novellino, E; Goegan, M; Mennini, T; Sullivan, S; Zisterer, DM; Williams, CD Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). J Med Chem 45:4276-81 (2002) [PubMed] Article
More Info.:
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rat
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE