Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15613
Substrate
n/a
Meas. Tech.
ChEMBL_122779 (CHEMBL730887)
Ki
11500±n/a nM
Citation
 Silvestri, R; La Regina, G; De Martino, G; Artico, M; Befani, O; Palumbo, M; Agostinelli, E; Turini, P Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. J Med Chem 46:917-20 (2003) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_BOVIN | Amine oxidase [flavin-containing] A | MAO-A | MAOA | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A
Type:
PROTEIN
Mol. Mass.:
59764.63
Organism:
Bos taurus
Description:
ChEMBL_1501477
Residue:
527
Sequence:
MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHVDYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKLRSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADRLAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAEDVPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
  
Inhibitor
Name:
BDBM15613
Synonyms:
4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | Aurorix | CHEMBL86304 | MCL | Moclobemide
Type:
Small organic molecule
Emp. Form.:
C13H17ClN2O2
Mol. Mass.:
268.739
SMILES:
Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Structure:
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