Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50470471
Substrate
n/a
Meas. Tech.
ChEMBL_2213714 (CHEMBL5126846)
Ki
1.2±n/a nM
Citation
 Saini, A; Patel, R; Gaba, S; Singh, G; Gupta, GD; Monga, V Adenosine receptor antagonists: Recent advances and therapeutic perspective. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Human
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50470471
Synonyms:
CHEMBL4294479
Type:
Small organic molecule
Emp. Form.:
C20H19N5O3
Mol. Mass.:
377.3966
SMILES:
CCc1ccc(COC(=O)c2cnc(NC)n3nc(nc23)-c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: