Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50610179
Substrate
n/a
Meas. Tech.
ChEMBL_2280318
Ki
>10.0±n/a nM
Citation
 Aranha, CMSQ; Reiner-Link, D; Leitzbach, LR; Lopes, FB; Stark, H; Fernandes, JPS Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H Bioorg Med Chem 78:0 (2023) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50610179
Synonyms:
CHEMBL5282002
Type:
Small organic molecule
Emp. Form.:
C19H24N2O2
Mol. Mass.:
312.4061
SMILES:
CN1CCN(CCCOC(=O)c2cccc3ccccc23)CC1
Structure:
Search PDB for entries with ligand similarity: