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Target
Probable G-protein coupled receptor 88
Ligand
BDBM50554975
Substrate
n/a
Meas. Tech.
ChEMBL_2280546
Ki
224±n/a nM
Citation
 Decker, AM; Rahman, MT; Kormos, CM; Hesk, D; Darcq, E; Kieffer, BL; Jin, C Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor. Bioorg Med Chem Lett 80:0 (2023) [PubMed] 
Target
Name:
Probable G-protein coupled receptor 88
Synonyms:
GPR88 | GPR88_HUMAN | Probable G-protein coupled receptor 88 | STRG | Striatum-specific G-protein coupled receptor
Type:
PROTEIN
Mol. Mass.:
40264.74
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109566
Residue:
384
Sequence:
MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAAAVAATAVPAVSQAQLGTRAAGQHW
  
Inhibitor
Name:
BDBM50554975
Synonyms:
CHEMBL4595209
Type:
Small organic molecule
Emp. Form.:
C28H33N3O3
Mol. Mass.:
459.5799
SMILES:
COCc1ccc(cc1)-c1ccc(cc1)N(C[C@@H](N)[C@@H](C)OC)C(=O)[C@@H]1C[C@H]1c1ccccn1 |r|
Structure:
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