Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM50212876
Substrate
n/a
Meas. Tech.
ChEMBL_455934 (CHEMBL887935)
Ki
4±n/a nM
Citation
 Sulsky, R; Magnin, DR; Huang, Y; Simpkins, L; Taunk, P; Patel, M; Zhu, Y; Stouch, TR; Bassolino-Klimas, D; Parker, R; Harrity, T; Stoffel, R; Taylor, DS; Lavoie, TB; Kish, K; Jacobson, BL; Sheriff, S; Adam, LP; Ewing, WR; Robl, JA Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg Med Chem Lett 17:3511-5 (2007) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Human
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50212876
Synonyms:
2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid | CHEMBL247298
Type:
Small organic molecule
Emp. Form.:
C21H14Cl4O4
Mol. Mass.:
472.145
SMILES:
OC(=O)c1cccc(OCc2ccc(Cl)cc2Cl)c1OCc1ccc(Cl)cc1Cl
Structure:
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