Found 1861 with Last Name = 'sheriff' and Initial = 's' 
Affinity DataKi: 0.0200nMAssay Description:Inhibition of human F11a using peptide substrate by spectrophotometryMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0980nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataKi: 0.140nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.150nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of recombinant human activated coagulation factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human activated factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human activated factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human activated factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of recombinant human activated coagulation factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Affinity for cloned Y2 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human coagulation factor 11a at 25 degCMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of recombinant human activated coagulation factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Competitive inhibition of human coagulation factor 11a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten eq...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Inhibition of human F11a using peptide substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
