Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50250299
Substrate
n/a
Meas. Tech.
ChEMBL_528821 (CHEMBL977663)
IC50
118100±n/a nM
Citation
 Deng, SChen, SNYao, PNikolic, Dvan Breemen, RBBolton, JLFong, HHFarnsworth, NRPauli, GF Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod 69:536-41 (2006) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Human
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50250299
Synonyms:
(9Z,11S,16R)-dihydroxyoctadeca-9,17-dien-12,14-diyn-1-yl acetate | 11(S),16(R)-dihydroxyoctadeca-9Z,17-diene-12,14-diyn-1-yl acetate | CHEMBL490698
Type:
Small organic molecule
Emp. Form.:
C20H28O4
Mol. Mass.:
332.4339
SMILES:
CC(=O)OCCCCCCCC\C=C/[C@H](O)C#CC#C[C@H](O)C=C |r|
Structure:
Search PDB for entries with ligand similarity: