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Target
Glycoprotein G
Ligand
BDBM50293782
Substrate
n/a
Meas. Tech.
ChEMBL_572058 (CHEMBL1024577)
EC50
>8000±n/a nM
Citation
 Niedermeier, S; Singethan, K; Rohrer, SG; Matz, M; Kossner, M; Diederich, S; Maisner, A; Schmitz, J; Hiltensperger, G; Baumann, K; Holzgrabe, U; Schneider-Schaulies, J A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion. J Med Chem 52:4257-65 (2009) [PubMed]  Article 
Target
Name:
Glycoprotein G
Synonyms:
G | GLYCP_NIPAV
Type:
PROTEIN
Mol. Mass.:
67048.85
Organism:
Nipah virus
Description:
ChEMBL_572058
Residue:
602
Sequence:
MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT
  
Inhibitor
Name:
BDBM50293782
Synonyms:
CHEMBL551697 | N-(4-Chlorobenzyl)-1-ethyl-4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide
Type:
Small organic molecule
Emp. Form.:
C20H16ClF3N2O2
Mol. Mass.:
408.801
SMILES:
CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2ccc(cc12)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: