Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM50293840
Substrate
n/a
Meas. Tech.
ChEMBL_572380 (CHEMBL1035281)
IC50
24100±n/a nM
Citation
 Ferri, N; Corsini, A; Bottino, P; Clerici, F; Contini, A Virtual screening approach for the identification of new Rac1 inhibitors. J Med Chem 52:4087-90 (2009) [PubMed]  Article 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1 | RAC1_HUMAN | Ras-related C3 botulinum toxin substrate 1 | Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 | TC25
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337921
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM50293840
Synonyms:
CHEMBL562095 | N-(4-methoxy-3-(piperidin-1-ylsulfonyl)phenyl)-1H-indazole-3-carboxamide
Type:
Small organic molecule
Emp. Form.:
C20H22N4O4S
Mol. Mass.:
414.478
SMILES:
COc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1S(=O)(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: