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Found 22 with Last Name = 'clerici' and Initial = 'f'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]paroxetine from SERT receptor in human platelet membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50223509((1R,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50223510((1S,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223508((1S,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50223511((1R,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223510((1S,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223509((1R,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223511((1R,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50223508((1S,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223509((1R,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223508((1S,2R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223510((1S,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50223511((1R,2S,4R)-1-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007190(CHEMBL3237589)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Rac1 in human MDA-MB-435 cells after 24 hrs by G-LISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293841(3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293840(CHEMBL562095 | N-(4-methoxy-3-(piperidin-1-ylsulfo...)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293842(1-(4-morpholinophenylamino)-1-oxopropan-2-yl 1-hyd...)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293843(1,8-diamino-6-methoxy-3-(4-(2-methoxyphenyl)pipera...)
Affinity DataIC50:  4.61E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293839(2-(4-fluoro-3-nitrophenylamino)-N-(4-morpholinophe...)
Affinity DataIC50:  5.72E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007189(CHEMBL3237582)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of Rac1 in human MDA-MB-435 cells after 24 hrs by G-LISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed