Reaction Details Report a problem with these data
Target
6,7-dimethyl-8-ribityllumazine synthase
Ligand
BDBM50316574
Substrate
n/a
Meas. Tech.
ChEMBL_631473 (CHEMBL1114707)
Ki
58000±n/a nM
Citation
Talukdar, A; Morgunova, E; Duan, J; Meining, W; Foloppe, N; Nilsson, L; Bacher, A; Illarionov, B; Fischer, M; Ladenstein, R; Cushman, M Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase. Bioorg Med Chem 18:3518-34 (2010) [PubMed] Article
More Info.:
Target
Name:
6,7-dimethyl-8-ribityllumazine synthase
Synonyms:
RISB_MYCTU | ribH
Type:
PROTEIN
Mol. Mass.:
16367.39
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
ChEMBL_631469
Residue:
160
Sequence:
MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS