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Target
Mu-type opioid receptor
Ligand
BDBM50326888
Substrate
n/a
Meas. Tech.
ChEMBL_662965 (CHEMBL1250824)
IC50
220±n/a nM
Citation
 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2. Eur J Med Chem 45:4594-600 (2010) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50326888
Synonyms:
(S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((R)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-3-sulfonamido)-3-phenylpropanamide | CHEMBL1253637
Type:
Small organic molecule
Emp. Form.:
C31H37N5O6S
Mol. Mass.:
607.72
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H](C1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Structure:
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