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Target
Platelet-activating factor receptor
Ligand
BDBM50282046
Substrate
n/a
Meas. Tech.
ChEBML_155135
IC50
190±n/a nM
Citation
 Wood, L; Whittaker, M; Timmis, DJ; Thompson, TM; Saroglou, L; Miller, A; Davidson, AH; Christodoulou, MS; Cackett, KS; Bowles, SA; Bebbington, DS Cyclic ether acetal platelet activating factor (PAF) receptor antagonists II: imidazo[4,5-c]pyridyl derivatives Bioorg Med Chem Lett 3:1499-1504 (1993)    Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM50282046
Synonyms:
2-Methyl-1-[3-(5-phenyl-tetrahydro-furan-2-yloxy)-propyl]-1H-imidazo[4,5-c]pyridine | CHEMBL36154
Type:
Small organic molecule
Emp. Form.:
C20H23N3O2
Mol. Mass.:
337.4155
SMILES:
Cc1nc2cnccc2n1CCCOC1CCC(O1)c1ccccc1
Structure:
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