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Found 171 with Last Name = 'davidson' and Initial = 'ah'
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290436((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50: <0.150nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  0.310nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290448((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  0.5nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290441((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  0.600nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290442((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  0.600nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290439((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  0.700nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290449((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  0.800nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290433((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290456((R)-2-Heptyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbam...)
Affinity DataIC50:  1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290450((R)-2-Dodecyl-N*4*-hydroxy-N*1*-((S)-1-methylcarba...)
Affinity DataIC50:  1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290436((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant Gelatinase B (MMP-9)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290453((R)-2-Decyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamo...)
Affinity DataIC50:  2nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50455629(CHEMBL487720)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280355(2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282045(1-{3-[5-(3-Chloro-4-methoxy-phenyl)-tetrahydro-fur...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290440((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  3nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280362((S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  4nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280356(2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  5nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  5nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282044(1-{3-[5-(3,4-Dichloro-phenyl)-tetrahydro-furan-2-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  6nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  6nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282036(1-{3-[(2S,5R)-5-(3,4-Dimethoxy-phenyl)-tetrahydro-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280350((S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282042(1-{3-[5-(4-Fluoro-phenyl)-tetrahydro-furan-2-yloxy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280364(2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282037(1-{3-[5-(4-Bromo-phenyl)-tetrahydro-furan-2-yloxy]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-Hexyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamo...)
Affinity DataIC50:  10nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005229(2-{[Acetyl-(5-octadecyloxy-tetrahydro-furan-3-ylme...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50455629(CHEMBL487720)
Affinity DataIC50:  12nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50406129(CHEMBL175236)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM81972((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM81972((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50004776(CHEMBL323880 | Sodium; 3,5-dihydroxy-7-[6-hydroxy-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280357(2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-3-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50280363(2,2-Dimethyl-pentanoic acid (1S,3S,4aR,7S,8S,8aS)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290446((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  15nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282036(1-{3-[(2S,5R)-5-(3,4-Dimethoxy-phenyl)-tetrahydro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290436((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290457((R)-2-Hexadecyl-N*4*-hydroxy-N*1*-((S)-1-methylcar...)
Affinity DataIC50:  20nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290457((R)-2-Hexadecyl-N*4*-hydroxy-N*1*-((S)-1-methylcar...)
Affinity DataIC50:  20nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282032(2-Methyl-1-{3-[5-(3,4,5-trimethoxy-phenyl)-tetrahy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290453((R)-2-Decyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamo...)
Affinity DataIC50:  20nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  20nMAssay Description:50% inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-Hexyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamo...)
Affinity DataIC50:  20nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  20nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

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