Affinity DataIC50: <0.150nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant Gelatinase B (MMP-9)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology
Curated by ChEMBL
British Bio-Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair