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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50002164
Substrate
n/a
Meas. Tech.
ChEMBL_202043 (CHEMBL809516)
IC50
1.5±n/a nM
Citation
 Perregaard, J; Moltzen, EK; Meier, E; Sánchez, C Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles. J Med Chem 38:1998-2008 (1995) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
Rat
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50002164
Synonyms:
3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole | CHEMBL59335
Type:
Small organic molecule
Emp. Form.:
C23H28N2
Mol. Mass.:
332.4818
SMILES:
C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1
Structure:
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