Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50373315
Substrate
n/a
Meas. Tech.
ChEMBL_467631 (CHEMBL930506)
Ki
7200±n/a nM
Citation
 Pfefferkorn, JA; Choi, C; Winters, T; Kennedy, R; Chi, L; Perrin, LA; Lu, G; Ping, YW; McClanahan, T; Schroeder, R; Leininger, MT; Geyer, A; Schefzick, S; Atherton, J P2Y1 receptor antagonists as novel antithrombotic agents. Bioorg Med Chem Lett 18:3338-43 (2008) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50373315
Synonyms:
CHEMBL255278
Type:
Small organic molecule
Emp. Form.:
C28H28N4O4
Mol. Mass.:
484.5463
SMILES:
COC(=O)c1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C(C)(C)C)n(n1)-c1ccccc1
Structure:
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