Reaction Details Report a problem with these data
Target
Capsid protein
Ligand
BDBM50248008
Substrate
n/a
Meas. Tech.
ChEMBL_1757270 (CHEMBL4192278)
EC50
>10000±n/a nM
Citation
 Sari, O; Boucle, S; Cox, BD; Ozturk, T; Russell, OO; Bassit, L; Amblard, F; Schinazi, RF Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector. Eur J Med Chem 138:407-421 (2017) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50248008
Synonyms:
BMS-200475-01 | Baraclude | CHEBI:473990 | Entecavir | SQ-34676
Type:
Small organic molecule
Emp. Form.:
C12H15N5O3
Mol. Mass.:
277.2792
SMILES:
Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)C1=C |r|
Structure:
Search PDB for entries with ligand similarity: