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Target
Mas-related G-protein coupled receptor member X1
Ligand
BDBM50412987
Substrate
n/a
Meas. Tech.
ChEMBL_1436304 (CHEMBL3388385)
EC50
<1995±n/a nM
Citation
 Hin, N; Alt, J; Zimmermann, SC; Delahanty, G; Ferraris, DV; Rojas, C; Li, F; Liu, Q; Dong, X; Slusher, BS; Tsukamoto, T Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorg Med Chem 22:5831-7 (2014) [PubMed]  Article 
Target
Name:
Mas-related G-protein coupled receptor member X1
Synonyms:
MRGX1_RAT | Mas-related G-protein coupled receptor member X1 | Mrgc | Mrgprc | Mrgprc11 | Mrgprx1 | Sensory neuron-specific G-protein coupled receptor 1 | Snsr | Snsr1
Type:
PROTEIN
Mol. Mass.:
37091.92
Organism:
Rattus norvegicus
Description:
ChEMBL_109489
Residue:
323
Sequence:
MDPTISSLSTESTTLNKTGHPSCRPILTLSFLVPIITLLGLAGNTIVLWLLGFRMRRKAISVYVLNLSLADSFFLCCHFIDSLMRIMNFYGIYAHKLSKEILGNAAIIPYISGLSILSAISTERCLSVLWPIWYHCHRPRNMSAIICVLIWVLSFLMGILDWFFSGFLGETHHHLWKNVDFIVTAFLIFLFMLLFGSSLALLVRILCGSRRKPLSRLYVTISLTVMVYLICGLPLGLYLFLLYWFGIHLHYPFCHIYQVTVLLSCVNSSANPIIYFLVGSFRHRKKHRSLKMVLKRALEETPEEDEYTDSHVQKPTEISERRC
  
Inhibitor
Name:
BDBM50412987
Synonyms:
CHEMBL475965
Type:
Small organic molecule
Emp. Form.:
C29H30N6O3
Mol. Mass.:
510.5869
SMILES:
COc1ccc(cn1)-c1ccc(cc1)C(=O)Nc1cccc(Cn2ncc(cc2=O)N2CCNCC2)c1C
Structure:
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