Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50283569
Substrate
n/a
Meas. Tech.
ChEMBL_79949 (CHEMBL687721)
IC50
18000±n/a nM
Citation
 Peyman, A; Stahl, W; Wagner, K; Ruppert, D; Budt, KH Non-peptide-based inhibitors of human immunodeficiency virus-1 protease Bioorg Med Chem Lett 4:2601-2604 (1994)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50283569
Synonyms:
4,6-Dibenzyl-1,3-bis-(4-bromomethyl-benzyl)-5-hydroxy-5-oxo-5lambda*5*-[1,3,5]diazaphosphinan-2-one | CHEMBL314409
Type:
Small organic molecule
Emp. Form.:
C33H33Br2N2O3P
Mol. Mass.:
696.408
SMILES:
OP1(O)=C(Cc2ccccc2)N(Cc2ccc(CBr)cc2)C(=O)N(Cc2ccc(CBr)cc2)C1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: