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Target
Kappa-type opioid receptor
Ligand
BDBM50304084
Substrate
n/a
Meas. Tech.
ChEMBL_601679 (CHEMBL1049577)
IC50
46±n/a nM
Citation
 Peng, Y; Zhang, Q; Arora, S; Keenan, SM; Kortagere, S; Wannemacher, KM; Howells, RD; Welsh, WJ Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways. Bioorg Med Chem 17:6442-50 (2009) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42692.90
Organism:
Rattus norvegicus (rat)
Description:
P34975
Residue:
380
Sequence:
MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50304084
Synonyms:
3-(2-(3-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol | CHEMBL605510
Type:
Small organic molecule
Emp. Form.:
C21H26N4O
Mol. Mass.:
350.4573
SMILES:
CN(C)Cc1nc(-c2cccc(O)c2)n(n1)-c1cccc(c1)C(C)(C)C
Structure:
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