Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM560331
Substrate
n/a
Meas. Tech.
Fluorescence Anisotropy Assay
Kd
420±n/a nM
Citation
 Brimert, T; Johnsson, R; Leffler, H; Nilsson, U; Zetterberg, F Galactoside inhibitor of galectins US Patent  US11377464 Publication Date 7/5/2022 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM560331
Synonyms:
3-Ethoxyphenyl 3-deoxy-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11377464, Example 3
Type:
Small organic molecule
Emp. Form.:
C22H22F3N3O5S
Mol. Mass.:
497.487
SMILES:
CCOc1cccc(S[C@H]2OC(CO)[C@H](O)C([C@@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)c1 |r|
Structure:
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