Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM560346
Substrate
n/a
Meas. Tech.
Fluorescence Anisotropy Assay
Kd
960±n/a nM
Citation
 Brimert, T; Johnsson, R; Leffler, H; Nilsson, U; Zetterberg, F Galactoside inhibitor of galectins US Patent  US11377464 Publication Date 7/5/2022 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM560346
Synonyms:
1-Naphthyl 3-deoxy-1-thio-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11377464, Example 18
Type:
Small organic molecule
Emp. Form.:
C24H20F3N3O4S
Mol. Mass.:
503.494
SMILES:
OCC1O[C@H](Sc2cccc3ccccc23)[C@@H](O)C([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r|
Structure:
Search PDB for entries with ligand similarity: