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Target
Neuraminidase
Ligand
BDBM575062
Substrate
n/a
Meas. Tech.
Assessing Antiviral Activity Against Influenza
IC50
>25000±n/a nM
Citation
 Remiszewski, S; Chiang, LW; Murphy, EA; Sun, Q; Kayser, F; Fink, SJ Broad spectrum antiviral compositions and methods US Patent  US11459321 Publication Date 10/4/2022 
Target
Name:
Neuraminidase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
50125.13
Organism:
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Description:
A0A1C9ZU71
Residue:
454
Sequence:
MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSSGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKIFKIEKGRVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIWDPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM575062
Synonyms:
US11459321, Example 8
Type:
Small organic molecule
Emp. Form.:
C27H27N7OS
Mol. Mass.:
497.615
SMILES:
COCCn1nncc1-c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)-n2cccn2)s1
Structure:
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