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Target
DNA gyrase inhibitor
Ligand
BDBM50542241
Substrate
n/a
Meas. Tech.
SDFQ HTS Assay
IC50
3125±n/a nM
Citation
 LENG, F; ALFONSO, E; DENG, Z; NEFZI, A; ROHDE, K BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF US Patent  US20230364057 Publication Date 11/16/2023 
Target
Name:
DNA gyrase inhibitor
Synonyms:
SBMC_ECOLI | gyrI | sbmC | yeeB
Type:
Protein
Mol. Mass.:
18071.67
Organism:
n/a
Description:
P33012
Residue:
157
Sequence:
MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
 
Inhibitor
Name:
BDBM50542241
Synonyms:
E127 | ERYTHROSINE | US20230364057, Compound 253
Type:
Small organic molecule
Emp. Form.:
C20H8I4O5
Mol. Mass.:
835.8924
SMILES:
Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C22OC(=O)c3ccccc23)c1I
Structure:
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