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Target
Transcription factor SOX-18
Ligand
BDBM223296
Substrate
n/a
Meas. Tech.
Inhibition of Sox18-DNA Binding Assay
IC50
3803000±1000 nM
Citation
 FRANCOIS, M; ZUEGG, J; OVERMAN, J; MAMIDYALA, SK; SALIM, AA; FONTAINE, FR; COOPER, MA; CAPON, RJ; ROBERTSON, AA COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT US Patent  US20240002326 Publication Date 1/4/2024 
Target
Name:
Transcription factor SOX-18
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
40895.30
Organism:
Human
Description:
P35713
Residue:
384
Sequence:
MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG
  
Inhibitor
Name:
BDBM223296
Synonyms:
Sm11 | US20240002326, Compound Sm11
Type:
Small organic molecule
Emp. Form.:
C15H14O5
Mol. Mass.:
274.2687
SMILES:
COc1ccc(OCC(=O)c2ccc(O)cc2O)cc1
Structure:
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