Reaction Details Report a problem with these data
Target
Programmed cell death 1 ligand 1
Ligand
BDBM644993
Substrate
n/a
Meas. Tech.
TBD
Kd
6530±n/a nM
Citation
 Suto, MJ; Mathew, B; Boohaker, R MODULATORS OF PROGRAMMED DEATH-LIGAND-1 US Patent  US20240010642 Publication Date 1/11/2024 
Target
Name:
Programmed cell death 1 ligand 1
Synonyms:
B7 homolog 1 | B7-H1 | B7H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PD1L1_HUMAN | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1
Type:
PROTEIN
Mol. Mass.:
33278.49
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109807
Residue:
290
Sequence:
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
  
Inhibitor
Name:
BDBM644993
Synonyms:
US20240010642, Example 22
Type:
Small organic molecule
Emp. Form.:
C18H26N4O3
Mol. Mass.:
346.424
SMILES:
CC(C)(NC(=O)C1(CCNCC1)NC(=O)Cc1ccccc1)C(N)=O
Structure:
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