Reaction Details Report a problem with these data
Target
Carbonic anhydrase 13
Ligand
BDBM33279
Substrate
BDBM10856
Meas. Tech.
CA Inhibition Assay
Ki
1125±n/a nM
Citation
 Vitale, RM; Alterio, V; Innocenti, A; Winum, JY; Monti, SM; De Simone, G; Supuran, CT Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors. J Med Chem 52:5990-8 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII
Type:
Enzyme
Mol. Mass.:
29522.80
Organism:
Mus musculus (mouse)
Description:
Murine cloned isozyme
Residue:
262
Sequence:
MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY
  
Inhibitor
Name:
BDBM33279
Synonyms:
CHEMBL24261 | aliphatic sulfamate, 1
Type:
Small organic molecule
Emp. Form.:
C8H19NO3S
Mol. Mass.:
209.306
SMILES:
CCCCCCCCOS(N)(=O)=O
Structure:
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Substrate
Name:
BDBM10856
Synonyms:
Carbon Dioxide | methanedione
Type:
Small organic molecule
Emp. Form.:
CO2
Mol. Mass.:
44.0095
SMILES:
O=C=O
Structure:
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