Affinity DataKi: 0.190nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of human recombinant carbonic anhydrase-7 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-1 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -51.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human recombinant carbonic anhydrase-7 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Inhibition of human recombinant carbonic anhydrase-7 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair